| 1. | Current IP Status: Complete patent application filed on 23rd June 2016 to Indian Patent Office, New Delhi.
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| 2. | Technology introduction and description: The technology relates to Genome wide identification of QTLs for milk yield in buffalo (Bubalus bubalis) using SNPs. A total of 6215 SNPs were discovered and genotyped in 12 sires and their daughters which constituted a reference family. The bulls were selected from the breed tract of Murrah buffaloes. The reference family was created for the purpose of identification of QTLs for milk yield. The phenotypic records of first lactation milk yield of 1762 buffalos were obtained and verified for normal distribution. The data was subjected to analysis using single marker analysis using QTL Cartographer, composite interval mapping using R/qtl and meta-QTL analysis using Biomercator. A total of 87 QTLs have been identified for the milk yield in buffaloes. The QTLs were present on all the autosomes except the q arm of BBU3 and p arm of BBU4. No QTL was identified on BBU19.
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| 3. | Benefits, usefulness, problem solving, business opportunities from the technology to the Client(s):
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| - QTLs shall enhance the accuracy of selection for milk yield as the trait is lowly heritable.
- High degree of accuracy as daughters on which phenotypes were generated had correct parentage.
- Identifies genomic markers along the chromosome responsible for the trait of interest in buffaloes.
- Evaluation of milk production traits of buffaloes during various stages of lactation.
- Identification of quantitative trait loci for milk yield in buffalo.
- Identification of chromosomal region associated with the QTL.
- The markers can be directly utilised for the selection of sires using linkage disequilibrium between two markers.
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| 4. | Prospective Client(s)/ Investors of the Technology: Large dairy farms, stake holders involved in enhancement of milk yield in buffaloes.
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| 5. | Expected price of the Technology: Negotiable .
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