| 1. | Current IP Status: Complete patent application filed on 23rd June 2016 to Indian Patent Office, New Delhi (application no. allotted is 201611021508).
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| 2. | Technology introduction and description(along with figures and graphics): Technology relates to identification of QTLs for increased/decreased somatic cell count in buffalo (Bubalus bubalis) using genome wide SNP markers. A total of 6215 SNPs were discovered and genotyped in 12 sires and their daughters which constituted a reference family. The bulls were selected from the breed tract of Murrah buffaloes. The reference family was created for the purpose of identification of QTLs for Somatic cell count. The phenotypic records for Somatic cell count from first lactation milk yield of 1762 buffalos were obtained and were log transformed and verified for normal distribution. The data was subjected to analysis using single marker analysis using QTL Cartographer, interval mapping /composite interval mapping using R/qtl and meta-QTL analysis using Biomercator. A total of 65 QTLs have been identified for the somatic cell score in buffaloes. The QTLs were present on all the autosomes except the p arm of BBU4 and autosome BBU6 and BBU19. This invention shall help in selection of sires for low somatic cell count for mastitis resistance in buffaloes.
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| 3. | Benefits, usefulness, problem solving, business opportunities from the technology to the Client(s):
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| - QTLs shall enhance the accuracy of selection for reducing incidence of mastitis as the trait is lowly heritable.
- High degree of accuracy as daughters on which phenotypes were generated had correct parentage.
- Identifies genomic markers along the chromosome responsible for the trait of interest in buffaloes.
- Identification of quantitative trait loci for somatic cell count in buffalo.
- Identification of chromosomal region associated with the QTL.
- The markers can be directly utilised for the selection of sires using linkage disequilibrium between two markers.
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| 4. | Prospective Client(s)/ Investors of the Technology: Large dairy farms, stake holders involved in control of mastitis.
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| 5. | Expected price of the Technology: Negotiable .
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